WebJun 1, 2024 · Located on chromosome band 6q23.1, the CTGF gene contains five exons and four introns, with each exon encoding a distinct module in the protein (Figure 1) … WebAug 15, 2009 · A rapid and dramatic reduction in the gene encoding connective tissue growth factor (CTGF) was observed in three-dimensional collagen culture. Connective tissue growth factor (CTGF) is a secreted molecule with many functions. It has been shown to participate in fibrogenesis, migration, proliferation, and adhesion 20-22.
Goat anti-CTGF IgG blocks TGF-stimulation of collagen
WebConnective Tissue Growth Factor. Connective tissue growth factor (CTGF) is a member of the CCN (CTGF, cysteine-rich angiogenic protein 61, and nephroblastoma overexpression gene) family of regulatory proteins. ... CTGF was originally found to promote fibroblast proliferation, migration, adhesion, and extracellular matrix formation as its … WebCTGF has multiple functions including promotion proliferation and differentiation of chondrocytes; mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells, and enhances fibroblast growth factor-induced DNA synthesis. oq é microsoft bing
CTGF regulates cell proliferation, migration, and glucose …
WebJun 1, 2016 · Age-dependent alterations in cardiac expression of adhesion molecules were suppressed in SPARC-null mice. A: gene array data of adhesion molecules. Table shows adhesion molecules, which changed with age in the left ventricle (LV) of wild type (WT) mice, including the ratio (old WT/young WT) and P value (old WT vs. young WT) of each … WebJan 26, 2006 · 1 Introduction. CCN family protein 2/connective tissue growth factor (CCN2/CTGF) regulates cell adhesion, migration, proliferation, survival, differentiation, and gene expression in a number of cell types isolated from tissues, including chondrocytes [].CCN2/CTGF is a member of the CCN family (Cyr61, CTGF, Nov); it is strongly … WebApr 13, 2024 · The identification of tissue-specific promoters for gene therapeutic constructs is one of the aims of complex tumor therapy. The genes encoding the fibroblast activation protein (FAP) and the connective tissue growth factor (CTGF) can function in tumor-associated stromal cells but are practically inactive in normal adult cells. Accordingly, the … oqb-c4701wzff 仕様書