WebDec 25, 2024 · 在这个过程中,细胞核中的组蛋白 3 ( His tone,H3 ) 经修饰形成瓜氨酸化的组蛋 白 3 ( Cit H3) ,进而使染色质由致密变得疏松并释放到胞外, 同时胞浆内的颗粒 … WebFeb 15, 2024 · Therefore, the anti–Cit-H3 antibody played only a limited pathologic role in this study, and controversies regarding the detection of ACPAs in mouse models of arthritis should be considered. Although our G-CSF–modified CIA model has some features seen in human RA, we need to be aware of the differences between human RA and this model.
NSAIDs起因性小腸傷害における好中球細胞外トラップの役割と診断・治療法確立
WebJan 9, 2024 · As neutrophil extracellular traps (NETs) are abundant in sepsis, neutralizing components of NETs may be a useful strategy to improve outcomes of sepsis. … WebJan 9, 2024 · Figure 1.CitH3 induces vascular leakage and formation of NETs. (A) HUVECs were treated with 1 μg/ml or 5 μg/ml of H3 peptide or CitH3 peptide for 16 h after forming … grand strand horseback riding
Neutrophil extracellular traps impair intestinal barrier ... - Nature
WebNov 13, 2014 · NETs and/or Cit-H3 were observed more frequently in "the presence of bacteria in tracheal aspirate" group (11/22, 50.0%) than in "the absence of bacteria in tracheal aspirate" group (4/27, 14.8%) (p<.01). Multiple logistic regression analysis showed that only the presence of bacteria in tracheal aspirate was significantly associated with … WebAug 1, 2014 · The ratio of Cit H3 positive stained cells to all cells was counted and calculated as mean values ± SD from 3 individual experiments. Animals. All research was conducted in compliance with the Animal Welfare Act, and was approved by the Animal Review Committee at the Massachusetts General Hospital. Male C57BL/6J mice (6–8 … WebApr 24, 2024 · The dichotomy between MPO-DNA and Cit-H3 levels in the COVID-19 sera tested here potentially suggests that 2 or more pathways to NETosis are active in … grand strand hospital directory